Class 12 topic wise Online MCQ with answers
Class 12 topic wise Online MCQ with answers
Topic: 4 Molecular Basis
OF Inheritance
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1. The final proof for DNA as
the genetic material came from the experiments of
(a) Hershey
and Chase
(b) Avery, MacLeod
and McCarty
(c) Hargobind
Khorana
(d) Griffith.
Answer:- (a) Hershey and Chase
2. ‘Origin of Species’ was written by
(a) Oparin
(b) Weismann
(c) Lamarck
(d) Darwin
Answer:- (d) Darwin
3. During DNA replication,
Okazaki fragments used to elongate
(a) the lagging strand towards replication fork
(b) the leading strand away from replication fork
(c) the lagging strand away from the replication fork
(d) the leading strand towards replication fork.
Answer:- (c) the lagging strand
away from the replication fork
4. Which of the following RNAs
should be most abundant in animal cell?
(a) tRNA
(b) mRNA
(c) miRNA
(d) rRNA
Answer:- (d) rRNA
5. Spliceosomes are not found
in cells of
(a) fungi
(b) animals
(c) bacteria
(d) plants.
Answer:- (c) bacteria
6. The association of histone
H 1 with a nucleosome indicates that
(a) DNA
replication is occurring
(b) the DNA
is condensed into a chromatin fibre
(c) the DNA
double helix is exposed
(d)
transcription is occurring.
Answer: - (b) the DNA is condensed into a chromatin fibre
7. Taylor conducted the experiments
to prove semiconservative mode of chromosome replication on
(a) Vinca
rosea
(b) Vicia
faba
(c)
Drosophila melanogaster
(d) E. coli.
Answer:- (b) Vicia
faba
8. The equivalent of a
structural gene is
(a) muton
(b) cistron
(c) operon
(d) recon.
Answer:- (b) cistron
9. Which of the following rRNAs
acts as structural RNA as well as ribozyme in bacteria?
(a) 5S rRNA
(b) 18S rRNA
(c) 23S rRNA
(d) 5.8S rRNA
Answer:- (b) 18S rRNA
10. A molecule that can act as
a genetic material must fulfill the traits given below, except
(a) it should be able to express itself in the form of ‘Mendelian
characters’
(b) it should be able to generate its replica
(c) it should be unstable structurally and chemically
(d) it should provide the scope for slow changes that are required
for evolution.
Answer:- (c) it should be unstable structurally and chemically
11. DNAdependent RNA
polymerase catalyses transcription on one strand of the DNA which is called the
(a) template
strand
(b) coding
strand
(c) alpha
strand
(d)
antistrand.
Answer:- (a) template strand
12. Which one of the following
is the starter codon?
(a) UAA
(b) UAG
(c) AUG
(d) UGA
Answer:- (c) AUG
13. Which of the following is
required as inducer (s) for the expression of Lac operon?
(a) Lactose
(b) Lactose
and Galactose
(c) Glucose
(d) Galactose
Answer:- (a) Lactose
14. A complex of ribosomes
attached to a single strand of RNA is known as
(a)
polypeptide
(b) Okazaki
fragment
(c) polysome
(d) polymer.
Answer:- (c) polysome
15. Which one of the following
is not applicable to RNA?
(a)
Heterocyclic nitrogenous bases
(b)
Chargaff’s rule
(c)
Complementary base pairing
(d) 5’ phosphoryl
and 3’ hydroxyl ends
Answer:- (b)
Chargaff’s rule
16. Balbiani rings are sites
of
(a)
polysaccharide synthesis
(b) RNA and
protein synthesis
(c) lipid
synthesis
(d)
nucleotide synthesis.
Answer:- (b) RNA and
protein synthesis
17. Identify the correct order
of organisation of genetic material from largest to smallest.
(a) Genome, chromosome, gene, nucleotide
(b) Chromosome, genome, nucleotide, gene
(c) Chromosome, gene, genome, nucleotide
(d) Genome, chromosome, nucleotide, gene
Answer:- (a) Genome, chromosome, gene, nucleotide
18. Satellite DNA is important
because it
(a) does not code for proteins and is same in all members of the
population
(b) codes for enzymes needed for DNA replication
(c) codes for proteins needed in cell cycle
(d) shows high degree of polymorphism in population and also the
same degree of polymorphism in an individual, which is heritable from parents
to children.
Answer:- (d) shows high degree of
polymorphism in population and also the same degree of polymorphism in an individual,
which is heritable from parents to children.
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19. Gene regulation governing
lactose operon of E.coli that involves the lac I gene product is
(a) negative and repressible because repressor protein prevents
transcription
(b) feedback inhibition because excess of Bgalactosidase can switch off transcription
(c) positive and inducible because it can be induced by lactose
(d) negative and inducible because repressor protein prevents
transcription.
Answer:- (d) negative and
inducible because repressor protein prevents transcription.
20. In sea urchin DNA, which
is double stranded, 17% of the bases were shown to be cytosine. The percentages
of the other three bases expected to be present in this DNA are
(a) G 17%, A 33%, T 33%
(b) G 8.5%, A 50%, T 24.5%
(c) G 34%, A 24.5%, T 24.5%
(d) G 17%, A 16.5%, T 32.5%.
Answer:- (a) G 17%, A 33%, T 33%
21. Which one of the following
is wrongly matched?
(a) Transcription Writing information from DNA to tRNA.
(b) Translation Using information in mRNA to make protein.
(c) Repressor protein Binds to operator to stop enzyme synthesis.
(d) Operon Structural genes, operator and promoter.
Answer:-
(a) Transcription Writing information from DNA to tRNA.
(b) Translation Using information in mRNA to make protein.
22. Transformation was
discovered by
(a) Meselson and Stahl
(b) Hershey and Chase
(c) Griffith
(d) Watson and Crick.
Answer:- (c) Griffith
23. Satellite RNAs are present in some
(a)
viroids
(b)
prions
c)
bacteriophages
(d)
plant viruses.
Answer:- (d)
plant viruses.
24. Which of the following
statements is not true of two genes that show 50% recombination frequency?
(a) The gene show independent assortment.
(b) If the genes are present on the same chromosome, they undergo
more than one crossovers in every meiosis.
(c) The genes may be on different chromosomes.
(d) The genes are tightly linked.
Answer:- (d) The genes are tightly
linked.
25. Which enzyme will be
produced in a cell if there is a nonsense mutation in the lac Y gene?
(a) Transacetylase
(b) Lactose permease and transacetylase
(c) beta galactosidase
(d) Lactose permease
Answer:- (c) beta galactosidase
26.
Which of the following is not a property of the
genetic code?
(a)
Nonoverlapping
(b)
Ambiguous
(c)
Degeneracy
(d)
Universal
Answer:- (b)
Ambiguous
27.
Genes of interest can be selected from a genomic
library by using……..
(a)
cloning vectors
(b)
DNA probes
(c)
gene targets
(d)
restriction enzymes.
Answer:- (b) DNA probes
28. One of
the most frequently used techniques
in DNA fingerprinting is
(a)
VNTR
(b)
SSCP
(c)
SCAR
(d)
AFLP.
Answer:- (a) VNTR
29.If one strand of DNA has the nitrogenous base
sequence as ATCTG, what would be the
complementary RNA strand sequence?
(a)
TTAGU
(b)
UAGAC
(c)
AACTG
(d)
ATCGU
Answer:- (b)
UAGAC
30. Which one
of the following is not a part
of a transcription unit in DNA?
(a)
The inducer
(b)
A terminator
(c)
A promoter
(d)
The structural gene
Answer:- (a)
The inducer
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Molecular Basis OF Inheritance online MCQ with answer
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